Friday, August 15, 2014

Briefly: rheumatoid arthritis in mice cured?

Briefly: rheumatoid arthritis in mice cured?

Researchers at the Federal Institute of Technology Zurich (ETH) managed to cure arthritis in mice. According to a statement released Thursday, they plan to test this new therapy on humans.

Rheumatoid arthritis is an inflammatory disease that results in particular in joint damage, which leads to quite dramatic distortions, as can attest to this deformed hand.  © James Heilman, Wikipedia, cc by sa 3.0

http://androidstars.newsvine.com/_news/2014/08/05/25184554-fly-the-mission-stardust
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http://carmiell.blogspot.com/2014/08/july-news-that-should-not-be-missed.html

The rheumatoid arthritis is inflammation of the joints very painful that affects about 1% of the world population. So far, there are only drugs that slow or stabilize the disease that causes the degeneration of cartilage and bone. A team of researchers at the Federal Institute of Technology Zurich (ETH) managed to completely cure mice with an antibody combined armed to one already available, the Dexamethasone.

If we apply only one or the other treatment, there is no effect. However, if both are administered simultaneously, the typical inflammation of the disease disappear in a few days. The discovery is described in an article published in  PNAS .

From next year, clinical trials are planned in patients with chronic arthritis. The project is supported by the Federal Commission for Technology and Innovation (CTI). Tests will be conducted by the biotechnology company Philochem, based near Zurich.

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